Synaptophysin (SYP) is an integral membrane glycoprotein of 38,000 Da and it has four membrane-spanning domains. Synaptophysin is localized to neurons, neuromuscular junctions, paraganglia cells, hypophysis, pancreatic islet cells, and adrenal cells. SYP gene is mapped to human chromosome Xp11.23. Monoclonal Anti-Synaptophysin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
Synonyms: Synaptophysin Antibody; Synaptophysin Antibody - Monoclonal Anti-Synaptophysin antibody produced in mouse
MDL Number: MFCD00164741
Storage: -20C
Application: Monoclonal Anti-Synaptophysin antibody has been used in western blotting.
Biochem Physiol Actions: Synaptophysin participates in calcium dependent exocytosis. The antibody detects synaptophysin in many types of benign and malignant neural and epithelial neuroendocrine neoplasms. It is widely used as a potential marker to study the circulation of synapses in the brain and to discover the basic features of the life cycle of synaptic vesicles (SVs).
Safety Statements (Europe): 36/37