MDL No.: MFCD00164716
Storage: -20C
UNSPSC Code: 12352203
General description: Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers . Monoclonal anti-plakoglobin (catenin γ) antibody specifically binds to plakoglobin (85kDa band and a possibly lower band) by immunoblotting. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.
Application: Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).
Immunogen: recombinant chicken plakoglobin.
RIDADR: NONH for all modes of transport
WGK Germany: 2
R Codes: 21/22
S Codes: 36/37-60
IOD Codes: Xn