Synonyms: Phospho-Tyr; Phospho-tyrosine; p-Tyr
MDL No.: MFCD00164715
Storage: -20C
UNSPSC Code: 12352203
General description: Protein phosphorylation is a post-translational modification that regulates signal transduction. Phosphorylation of tyrosine residues in proteins has been associated with oncogenesis, cell growth and survival . Monoclonal Anti-Phosphotyrosine antibody is specific for rat and human proteins/peptides that contain phosphotyrosine residues. As determined by competitive ELISA, the product does not bind to non-phosphorylated tyrosine, phosphorylated serine or threonine, ATP or AMP.
Application: Suitable for use in western blot (1:2000 using crude extracts from dissected rat tissue or from transfected HEK293 cells ). The product can also be used for immunohistochemistry, direct ELISA and microarray.
Immunogen: tyrosine phosphorylated peptide.
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
RIDADR: NONH for all modes of transport