Synonyms: Anti-Poly(A)-Binding Protein
MDL No.: MFCD06412253
Storage: -20C
UNSPSC Code: 12352203
General description: Poly(A) binding protein (PABP) possesses RNA recognition motifs (RRMs), a proline-rich region and a PABP C-terminal domain. The gene encoding this protein is localized on human chromosome 8q22.3.
Application: Monoclonal Anti-PABP antibody produced in mouse has been used for immunofluorescence.
Biochem/physiol Actions: Poly(A) binding protein (PABP) has a role in mRNA translation and stability. It modulates gene expression. The protein binds to the poly(A) tail, bridges the ends of mRNA and forms a closed loop. This might help in translation initiation by promoting ribosome recruitment.
Immunogen: recombinant human PABP.
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: nwg