Synonyms: Fibroblast Surface Protein Antibody; Fibroblast Surface Protein Antibody - Monoclonal Anti-Fibroblast Surface Protein antibody produced in mouse
MDL No.: MFCD00164646
Storage: -20C
UNSPSC Code: 12352203
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General description: Human fibroblast surface protein is a fibroblast antigen that is expressed mainly on human synovial, foreskin and thymic fibroblasts and is absent on human epithelial cells and lymphocytes. Monoclonal anti-fibroblast surface protein antibody can be used in immunohistological staining of frozen sections of human tissue. It is also used to remove fibroblasts from human cultured cells by inhibiting fibroblasts adherence to the culture vessel or by cytotoxic effect in the presence of rabbit complement. Monoclonal anti-human fibroblast surface protein antibody reacts specifically with surface protein of human fibroblasts and fibroblast cell lines. It has also shown reactivity for tissue macrophages and 95% of peripheral blood monocytes.
Application: Monoclonal anti-fibroblast surface protein antibody can be used in flow cytometry of human fibroblasts and monocytes. It is also useful in immunoblotting and western blotting.
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunofluorescence (1 paper)Immunohistochemistry (1 paper)
Immunogen: cultured human thymic fibroblasts
Target description: This fibroblast antigen has been demonstrated on human synovial, mammary, foreskin and thymic fibroblasts and in malignant fibrosarcoma tissue. The antigen is both cell membrane and lysosome associated.
Analysis Note: Working dilution is at least 1:500 by complement-mediated microcytotoxicity assay.
RIDADR: NONH for all modes of transport
WGK Germany: 2
R Codes: 21/22
S Codes: 36/37-60
IOD Codes: Xn