Monoclonal Anti-Factor IX antibody produced in mouse, clone HIX-5, purified from hybridoma cell culture

Synonyms: Anti-Factor IX antibody, Mouse monoclonal

MDL No.: MFCD00162406

Storage: -20C

UNSPSC Code: 12352203

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Application: Monoclonal Anti-Factor IX antibody produced in mouse is suitable for indirect ELISA and western blotting at a dilution of 1:500.

Biochem/physiol Actions: Four and a half LIM domains protein 1 is a protein encoded by the FHL1 gene in human and located on human chromosome Xq27.2. Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system. It belongs to peptidase family S1 and its deficiency causes hemophilia B. The proteins belong to a novel family of LIM proteins that are expressed in human skeletal muscle. FHL1 gene is related to carcinogenesis and its inactivation is a frequent event during oral carcinogenesis. FHL1 downregulation in oral squamous cell carcinoma (OSCC) occurs through DNA methylation of the promoter region rather than histone deacetylation or mutation.

Immunogen: Factor IX from pooled normal human plasma.

Physical form: Solution in 10 mM HEPES, pH 7.4, with 140 mM sodium chloride and 0.05% sodium azide.