Synonyms: Anti-EGFR
MDL No.: MFCD00162282
Storage: -20C
UNSPSC Code: 51111800
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Application: Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse was used for immunoblotting using lysates of mouse liver cells for in vivo protein kinase assay.
Biochem/physiol Actions: EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer.
Immunogen: synthetically produced residues 985-996 of the human EGF receptor.
Specificity: This antibody recognizes specifically an intracellular domain of the EGF receptor.
RIDADR: NONH for all modes of transport
WGK Germany: 2
R Codes: 21/22
S Codes: 36/37-60
IOD Codes: Xn