Synonyms: Monoclonal Anti-Cytokeratin Peptide 18
MDL No.: MFCD00162250
Storage: -20C
UNSPSC Code: 12352203
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Application: Monoclonal Anti-Cytokeratin Peptide 18-FITC antibody:. is suitable for immunohistochemistry to identify renal tubular epithelial cells in the extrarenal cells regeneration during acute renal failure. . is suitable for immunocytochemical and immuno-electron microscopic localisation of keratins in human materno-foetal interaction zone. . may be used for single or double labeling procedures.
Biochem/physiol Actions: Cytokeratins also called keratins (Ks) according to the new nomenclature system.These are known to be the major structural proteins of epithelial cells. It is heteropolymeric in nature i.e. in cells more than one keratin protein is always present. It belongs to type I acrylic sub-family and is differentially expressed in various human tissues. It maintains the structural integrity of extra-embryonic membrane epithelia. Broadly keratins are grouped into two types on the basis of their biochemical and immunological properties: Type II keratins are a family of basic proteins identified as K1 to K8, whereas type I keratins consists of K9 to K20, belong to the acidic group.
Immunogen: human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 0.01% thimerosal.
RIDADR: NONH for all modes of transport