Synonyms: Monoclonal Anti-CD56; Anti-NKH-1
MDL No.: MFCD02263245
Storage: 2-8C
UNSPSC Code: 12352203
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General description: Prepared by conjugation of fluorescein isothiocyanate isomer 1 (FITC). This green dye is efficiently excited at 495 nm and emits at 525 nm.
Application: Monoclonal Anti-CD56-FITC antibody produced in mouse is suitable for fluorescence microscopy. It was also used for flow cytometric analysis.
Biochem/physiol Actions: Neural Cell Adhesion Molecule (NCAM or the cluster of differentiation CD56) is a homophilic binding glycoprotein. It is expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. CD56 can also be expressed in normal immature granulocytes at different expression levels in regenerative bone marrow. It is associated with cardiac genes induced by metabolic stress and its expression is associated with worsening hemodynamic parameters and major metabolic genes. CD56 is involved in left ventricular remodeling and can be implicated in heart failure. It is is developmentally regulated and may have an important role in cardiac development.
Immunogen: A cloned human NK cell line termed JT3
Physical form: Solution in phosphate buffered saline, pH 7.4, containing 0.2% gelatin and 0.08% sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: 1