ß-amyloid gene is located on human chromosome 21q21.
Synonyms: Anti-A-BETA; Anti-Amyloid beta Precursor Protein; Clone BAM91
MDL Number: MFCD00803867
Storage: -20C
Application: The antibody is useful in immunohistochemistry, immunoblotting, ELISA, and competitive ELISA. Also, this antibody has been used to neutralize Aß assemblies in brains of transgenic mice expressing a mutant form of amyloid precursor protein, and for in vivo deep tissue imaging using near-IR optical spectrum.
Biochem Physiol Actions: ß-amyloid gene acts as the substrate of insulin-degrading enzyme (IDE). It plays a major role in the pathogenesis of Alzheimer's disease (AD) and type 2 diabetes mellitus (DM2).