MDL No.: MFCD00164521
Storage: -20C
UNSPSC Code: 12352203
General description: Actin is a cytoskeletal protein that regulates cell motility, secretion, phagocytosis and cytokinesis. The NH2-terminal of actin may function as antigen. This terminal may also modulate actin interactions and may associate with proteins such as myosin. Mouse monoclonal anti-actin (α-sarcomeric) antibody is specific for α-skeletal and α-cardiac muscle actins as characterized by ELISA, immunoblot and immunohistochemistry. The antibody shows wide species cross reactivity with tissue from human, sheep, bovine, rabbit, guinea pig, rat, frog, snake, and carp. However, it does not react with smooth muscle tissue.
Application: Mouse monoclonal anti-actin (alpha-sarcomeric) antibody has been used for western blot, and immunohistochemistry applications. The antibody can also be used for indirect ELISA.
Application: Monoclonal mouse anti-actin antibody was used as a loading control for western blot analysis of immunoprecipitated proteins from rat dorsal root ganglion cocultures.
Immunogen: rabbit striated muscle actin.
Physical form: The product is provided as ascites fluid containing 0.1% sodium azide as a preservative.
Other Notes: To view an Actin antibody selection guide, please visit www.sigmaaldrich.com/actin.
RIDADR: NONH for all modes of transport
WGK Germany: 3