Synonym(s): 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt; Sodium levothyroxine; T4
Formula: HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Formula Weight: 888.93
CAS No.: 6106-07-6
Purity: ≥98%
Physical form: powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days
Storage: −20°C
Beilstein Registry Number: 5721845
EC No.: 200-221-4
Melting Point: 207-210 (dec.)(lit.)
Biochem/physiol Actions: L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.
Reconstitution: To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium.
Empirical Formula (Hill Notation): C9H11ClO2S