Synonyms: Aminoformamidine hydrochloride; Aminomethanamidine hydrochloride; Guanidinium chloride
Molecular Formula: CH5N3 · HCl
Molecular Weight: 95.53
Linear Structural Formula: NH2C(=NH)NH2 · HCl
MDL Number: MFCD00013026
Purity: >=99%
Melting Point: 180-185 C (lit.)
Density: 1.3 g/cm3 (lit.)
Application: Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Legal Information: Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
Safety Statements (Europe): 22
Signal Word: Warning
Hazard statements: H302-H315-H319
Precautionary statements: P305 + P351 + P338