Synonyms: (3-(Formylhydroxyamino)propyl)phosphonic acid sodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; FR 31564
CAS Number: 66508-53-0 (free base)
Formula: C4H10NO5P · xNa+ · yH2O
Formula Weight: 183.10 (anhydrous free acid basis)
Linear Formula: C4H10NO5P · xNa+ · yH2O
Purity: >=95% (NMR)
Storage: -20C
UNSPSC Code: 12352200
Features and Benefits: This compound is also offered as part of Sigma's Library of Pharmacologically Active Compounds (LOPAC(R)1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
Biochem/physiol Actions: Fosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) (MEP synthase): an antimalarial compound. 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway).
RIDADR: NONH for all modes of transport
WGK Germany: 3