ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO(R) Kinase, >=70% (SDS-PAGE), buffered aqueous glycerol solution

Synonyms: ERT1; MAPK1; MAPK2; P41mapk; P42MAPK; PRKM1; PRKM2; p40; p47

Purity: >=70% (SDS-PAGE)

Activity: activity: 613-829 nmol/min·mg

Storage: -70C

UNSPSC Code: 12352200

Biochem/physiol Actions: ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

Physical form: Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.