Synonyms: CoA
Formula: C21H36N7O16P3S · xH2O
Formula Weight: 767.53 (anhydrous basis)
CAS No.: 85-61-0 (anhydrous)
Purity: ≥85% (UV, HPLC)
Storage Temperature: −20°C
Biochem/physiol Actions: Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.
Caution: The free acid is less stable than the sodium or lithium salt; 5% decomposition may occur within 6 months when stored at −20 °C.