Synonyms: D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide; Chloromycetin
Formula: Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
Formula Weight: 323.13
CAS No.: 56-75-7
Application: Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.
Biochem/physiol Actions: Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.
Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
Protocols & Applications: Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Gene Information: human ... CYP1A2
Impurities: Endotoxin, tested
MP: 148-150°C(lit.)
Product Line: BioReagent
Suitability: suitable for plant cell culture