Apolipoprotein A-II from human plasma, >=95% (SDS-PAGE), buffered aqueous solution

Synonyms: Apo A-II

MDL No.: MFCD00132612

Purity: >=95% (SDS-PAGE)

Storage: -20C

UNSPSC Code: 12352200

General description: Forms dimers in aqueous solutions with an association constant of 5 x 104 M-1. The association is accompanied by an enhancement of ~35% in alpha-helical content.

Application: Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

Biochem/physiol Actions: Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

Physical form: Solution in 10 mM ammonium bicarbonate.