Uncoupling protein (UCP1) is a 32 kDa, mitochondrial inner membrane protein. It is active as a proton channel forming dimer. It can bind purine nucleotides and is capable of being stimulated by fatty acids.
Synonyms: Ucp1 Antibody; Ucp1 Antibody - Anti-UCP-1 antibody produced in rabbit; Anti-Uncoupling Protein 1
MDL Number: MFCD01092514
Storage: -20C
Application: Anti-UCP-1 antibody produced in rabbit has been used in western blotting and immunohistochemistry.
Biochem Physiol Actions: Uncoupling proteins (UCPs) are transporters functioning as enzymatic uncouplers of oxidative phosphorylation. They can return protons pumped by the respiratory chain to the mitochondrial matrix. UCP-1 is exclusively expressed in brown adipose tissue (BAT) in rodents and in neonates where it is regulated by norepinephrine and thyroid hormones. UCP-1 has been shown to depend on CoQ (ubiquinone) as an obligatory co-factor.