Synonyms: Anti-Erp58; Anti-PDI
MDL No.: MFCD01094568
Storage: -20C
UNSPSC Code: 12352203
General description: Prolyl 4-hydroxylase subunit β (P4HB) is a redox-regulated thiol-containing protein. The gene encoding this protein is localized on human chromosome 17q25.3.
Biochem/physiol Actions: Prolyl 4-hydroxylase subunit β (P4HB) acts as a molecular chaperone in the endoplasmic reticulum of cells and also as an oxidoreductase. It associates with steroid hormones and modulates their actions, concentrations and storage. P4HB accelerates the formation of disulphide bonds in proteins and hence aids in their folding.
Immunogen: synthetic peptide corresponding to amino acid residues 498-508 of human protein disulfide isomerase.
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.