Anti-Protein Disulfide Isomerase antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Synonyms: Anti-Erp58; Anti-PDI

MDL No.: MFCD01094568

Storage: -20C

UNSPSC Code: 12352203

General description: Prolyl 4-hydroxylase subunit β (P4HB) or protein disulfide isomerase is a redox-regulated thiol-containing protein. The gene encoding this protein is localized on human chromosome 17q25.3.

Application: Anti-Protein Disulfide Isomerase antibody produced in rabbit has been used in immunofluorescence.

Biochem/physiol Actions: Prolyl 4-hydroxylase subunit β (P4HB) or protein disulfide isomerase acts as a molecular chaperone in the endoplasmic reticulum of cells and also as an oxidoreductase. It associates with steroid hormones and modulates their actions, concentrations and storage. P4HB accelerates the formation of disulphide bonds in proteins and hence aids in their folding.

Immunogen: protein disulfide isomerase purified from bovine liver.

Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.