Synonyms: Anti-Interferon-induced, double-stranded RNA-activated protein kinase (ET-20)
MDL No.: MFCD04040533
Storage: -20C
UNSPSC Code: 12352203
General description: PKR is a double-stranded RNA-dependent serine/threonine kinase that regulates antiproliferative and antiviral functions of interferons. PKR also functions as a translational inhibitor. In genotoxic environments, PKR mediates CDC2 ubiquitination and G2 arrest in cells . Anti-PKR is antibody is specific for human PKR (68 kDa).
Application: Anti-PKR (ET-20) antibody I suitable for use in western blot (1:2,000 using a whole cell extract of the human epitheloid carcinoma HeLa cell line induced with interferon-gamma) and microarray.
Immunogen: C-terminus of human PKR (amino acids 531-550), conjugated to KLH
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide