Synonyms: Leptin Antibody; Leptin Antibody - Anti-Leptin antibody produced in rabbit; Anti-OB
MDL No.: MFCD00803408
Storage: -20C
UNSPSC Code: 12352203
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Western Blotting (1 paper)
Application: Anti-Leptin antibody produced in rabbit was used in western blotting of total protein extracted from intra-abdominal fat pad of mice.
Biochem/physiol Actions: Leptin is a hormone secreted by adipocytes and regulates energy homeostasis, inflammation and neuroendocrine processes, synaptic formation and memory condensation. The physiological effects of leptin are mediated by leptin receptors, ObR and LepR. Leptin is the key regulator of obesity and acts directly on neuronal networks to regulate feeding, metabolism, gastric mobility and energy homeostasis. The pathways that mediate the effect of leptin are JAK/STAT, PI3K and JNK.
Immunogen: synthetic peptide corresponds to the amino terminal (amino acid residues 22-40) of human/mouse leptin.
Physical form: Solution in phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.
Preparation Note: The antibody is affinity isolated on peptide-agarose.
RIDADR: NONH for all modes of transport
WGK Germany: 3