MDL No.: MFCD00162464
Storage: -20C
UNSPSC Code: 12352203
General description: B cells predominantly secrete IgM antibodies as pentamers, but may also secrete them as hexamers which are capable of activating the complement cascade more efficiently. Goat anti-human IgM (mu-chain specific)-peroxidase antibody is specific for human IgM and does not bind to other human Igs. Furthermore, the antibody does not react with mouse and rat IgG. Hence, the antibody conjugate yields reduced background with mouse or rat samples.
Application: Anti- Human IgM was used in an ELISA assay to determine the concentration of IgM secreted by CH12 B lymphoma cells stimulated by LPS.
Immunogen: human IgM
Physical form: Solution in 0.01 M phosphate buffered saline pH 7.4, containing 0.01% thimerosal
Preparation Note: Prepared by the two-step glutaraldehyde method described by Avrameas, S., et al., Scand. J. Immunol., 8, Suppl. 7, 7 (1978).
RIDADR: NONH for all modes of transport
WGK Germany: 3