MDL No.: MFCD00162406
Storage: -20C
UNSPSC Code: 12352203
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Application: Anti-Factor IX antibody produced in rabbit is suitable for the following applications:. Dot blot analysis at a dilution of 1:8,000. Indirect ELISA at a dilution of 1:5,000. Western blotting at a dilution of 1:3,000 using using reduced and non-reduced human plasma blots
Biochem/physiol Actions: Four and a half LIM domains protein 1 is a protein encoded by the FHL1 gene in humans and is located on human chromosome Xq27.2. Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system. It belongs to peptidase family S1 and its deficiency causes hemophilia B. The proteins belong to a novel family of LIM proteins that are expressed in human skeletal muscle. FHL1 gene is related to carcinogenesis and its inactivation is a frequent event during oral carcinogenesis. FHL1 downregulation in oral squamous cell carcinoma (OSCC) occurs through DNA methylation of the promoter region rather than histone deacetylation or mutation.
Immunogen: human factor IX
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Specificity: Specifically reacts with human factor IX. The antibody detects human factor IX in both reduced and non-reduced normal human plasma.
RIDADR: NONH for all modes of transport
WGK Germany: nwg