MDL No.: MFCD01633332
Storage: -20C
UNSPSC Code: 12352203
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General description: Extracellular signal-regulated kinase 5 (ERK5), also referred to as big-MAP kinase 1 or BMK1, is a protein that belongs to Mitogen-activated protein kinases family and is expressed mainly in skeletal muscle, kidney, heart and placenta. It has a critical role in different cellular processes like differentiation, proliferation and survival. Anti-ERK5 (big-MAPK, BMK1) antibody can be used to study the differential tissue expression and intracellular localization of the MAP Kinase isoform in normal and neoplastic tissues. Rabbit anti-ERK5 (big-MAPK, BMK1) antibody reacts specifically with ERK5 (97 kD) from mouse fibroblast cell extract.
Application: Anti-ERK5 (big-MAPK, BMK1) antibody can be used in immunoblotting to detect and localize ERK5 from whole cell extract of NIH 3T3 mouse fibroblasts. It can also be used in microarray.
Immunogen: synthetic peptide corresponding to amino acids 789-802 of human ERK5.
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: 3
R Codes: 21/22
S Codes: 36/37
IOD Codes: Xn