Synonyms: Anti-DCDC2A; Anti-RU2; Anti-RU2S
Storage: -20C
UNSPSC Code: 12352203
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General description: DCDC2 belongs to the doublecortin (DCX) superfamily and contains two doublecortin domains. DCDC2 is expressed in fetal and adult CNS.
Application: Anti-DCDC2 antibody produced in rabbit is suitable for western blot analysis at a working concentration of 0.5-1mug/mL using a HEK-293T cell lysate expressing human DCDC2.
Biochem/physiol Actions: DCDC2 is one of the dyslexia susceptibility genes involved in neuronal migration and other developmental processes. The DCX domain of DCDC2 binds tubulin and enhances microtubule polymerization. Several SNPs within the DCDC2 gene have been associated with dyslexia. It modulates neuronal development in the brain.
Immunogen: synthetic peptide corresponding to amino acids 351-368 of human DCDC2, conjugated to KLH.
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
RIDADR: NONH for all modes of transport