Synonyms: Anti-Caveolin-1; Anti-VIP21
MDL No.: MFCD01633097
Storage: -20C
UNSPSC Code: 12352203
General description: Caveolin, a 20-24-kDa integral transmembrane protein, has been identified as a principal component of caveolae membranes. Caveolin (also termed VIP21) exists in several isoforms termed caveolin-1, caveolin-2 and caveolin-3. Caveolin-1 (20-22 kDa) can exist as two isoforms, caveolin-1alpha and -1beta due to alternative splicing of the mRNA. Anti-Caveolin-1 is developed in rabbit using a synthetic peptide corresponding to a region at the N-terminus of human caveolin-1 (amino acids 2-20) conjugated to KLH as immunogen.
Application: Anti-Caveolin-1 antibody produced in rabbit is suitable for indirect immunofluorescence using mouse fibroblast NIH3T3 cell line. It is suitable for microarray. Anti-Caveolin-1 is also suitable for western blot using whole cell extract of the human umbilical vein endothelial HUVEC cell line and the rat fibroblast Rat-1 cell line
Immunogen: synthetic peptide corresponding to a region at the N-terminus of human caveolin-1 (amino acids 2-20).
Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Specificity: The sequence is highly conserved in many species, e.g., identical in rat, mouse, bovine, and dog caveolin-1. The sequence is not found in caveolin-2 or caveolin-3.
RIDADR: NONH for all modes of transport
WGK Germany: 3