Synonyms: ACE; Peptidyl-dipeptidase A
CAS Number: 9015-82-1
MDL No.: MFCD00130325
Storage: -20C
Enzyme Commission (EC) Number: 3.4.15.1 ( BRENDA | IUBMB )
UNSPSC Code: 12352200
General description: ACE is a monomer with molecular weight of ~170 kDapH range for activity: 7-8.5 Temperature optimum: 37 CZinc is required for activityInhibitors: captopril, enalaprilat, lisinopril etc. (1-10 muM)
Biochem/physiol Actions: Removes C-terminal dipeptides from susceptible substrates, e.g., angiotensin I and bradykinin.
Physical form: Lyophilized powder containing Tris buffer salts.
Unit Definition: One unit will produce 1.0 ·mumole of hippuric acid from Hippuryl-His-Leu per min in 50 mM HEPES and 300 mM NaCl at pH 8.3 at 37 C.
RIDADR: NONH for all modes of transport
WGK Germany: 3