AMPK (alpha1/beta1/gamma1), active, His tagged human, PRECISIO(R) Kinase, recombinant, expressed in baculovirus infected Sf9 cells, >=70% (SDS-PAGE), buffered aqueous glycerol solution

Synonyms: AMPKG; HAMPKb; MGC17785; MGC33776; MGC57364; MGC8666; PRKAA1; PRKAB1; PRKAG1

Purity: >=70% (SDS-PAGE)

Activity: activity: 626-848 nmol/min·mg

Storage: -70C

UNSPSC Code: 12352200

Biochem/physiol Actions: AMPK is a heterotrimer protein kinase consisting of a α catalytic subunit, and non-catalytic β and γ subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol.

Physical form: Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.