Synonym(s): Fungizone
Formula: C47H73NO17
Formula Weight: 924.08
CAS No.: 1397-89-3
Purity: ~80% (HPLC)
Application: Recommended for antifungal use in cell culture media at 2.5 mg/L. Stable at 37 °C for 3 days.
Storage: 2-8°C
Beilstein Registry Number: 78342
EC No.: 215-742-2
Biochem/physiol Actions: Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out.
Antimicrobial spectrum: fungi and yeast.