Synonyms: (2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrochloride hydrate
CAS Number: 100938-10-1
Formula: C21H38N4O8 · HCl · xH2O
Formula Weight: 511.01 (anhydrous basis)
Linear Formula: C21H38N4O8 · HCl · xH2O
MDL No.: MFCD00150636
Purity: >=97% (HPLC)
Storage: -20C
Beilstein Registry Number: 8888370
UNSPSC Code: 12352202
General description: Chemical structure: peptide
Biochem/physiol Actions: It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.
Biochem/physiol Actions: It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.
RIDADR: NONH for all modes of transport
WGK Germany: 3