Adenosine 3'-phosphate 5'-phosphosulfate lithium salt hydrate, >=60%

Synonyms: 3'-Phosphoadenosine 5'-phosphosulfate lithium salt; APPS; Active sulfate; PAPS

CAS Number: 109434-21-1

Formula: C10H15N5O13P2S · xLi+ · yH2O

Formula Weight: 507.26 (free acid basis)

Linear Formula: C10H15N5O13P2S · xLi+ · yH2O

Purity: >=60%

Storage: -70C

Beilstein Registry Number: 8181191

UNSPSC Code: 41106305

Application: Adenosine 3′-phosphate 5′-phosphosulfate lithium salt has been used in a study that cloned and characterized a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate. Adenosine 3′-phosphate 5′-phosphosulfate lithium salt has also been used in a study to assess the golgi-resident PAP-specific 3′-phosphatase-coupled sulfotransferase assays.

Application: 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) is used as a universal sulfonate donor for in vivo sulfonation by sulfotransferases. PAPS is used for the sulfation of glycans. PAPS is also useful to study the distribution and function of its biological transporter(s).

Quality: Major impurities appear to be adenosine 3′,5′-diphosphate, sulfate and ammonia substitution products.

Other Notes: Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A1651.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.