Formula: C26H24N2O4
Formula Weight: 428.48
Linear Formula: C26H24N2O4
Storage: -20C
UNSPSC Code: 12352204
Biochem/physiol Actions: The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease.
Biochem/physiol Actions: Diacylglycerol acyltransferase (DGAT-1) inhibitor; IC50 7 to 24 nM
Physical form: A922500 is supplied as a crystalline solid.
Preparation Note: A stock solution may be made by dissolving the A922500 in the solvent of choice. A922500 is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF).
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
R Codes: 25-36-50
S Codes: 26-45-61
IOD Codes: T,N
Symbol: GHS06, GHS09
Signal Word: Danger
Hazard Statements: H301-H319-H410
Precautionary statements: P273-P301 + P310-P305 + P351 + P338-P501