Synonym(s): 2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol
Formula: C5H5N5S
Formula Weight: 167.19
CAS No.: 154-42-7
UN Number: UN2811
Purity: ~98%
Application: Used in hybridoma formation applications as a selection agent.
Legal Information: Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Beilstein Registry Number: 157765
EC No.: 205-827-2
Melting Point: ≥300°C(lit.)
Biochem/physiol Actions: Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.1
Reconstitution: Reconstitute contents of vial with 10 ml sterile cell culture medium. Stock solution is sufficient to prepare 500 ml medium. Final working concentration: 30 μM 2-amino-6-mercaptopurine.
Empirical Formula (Hill Notation): C6H4ClNO2