Synonym(s): 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; Ladakamycin
Formula: C8H12N4O5
Formula Weight: 244.20
CAS No.: 320-67-2
Application: Used to study the effects of the DNA incorporated molecule on DNA methylation processes.
Legal Information: Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Storage: −20°C
Beilstein Registry Number: 620461
EC No.: 206-280-2
Melting Point: 226-232°C (dec.)(lit.)
Biochem/physiol Actions: A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing.
Reconstitution: Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500ml medium. Final working concentration: 10 μM 5-azacytidine.
Empirical Formula (Hill Notation): C4F12N2O8S4Zn