20S Proteasome Fraction from rabbit, >=95% (SDS-PAGE), solution

MDL No.: MFCD01091499

Purity: >=95% (SDS-PAGE)

Storage: -70C

UNSPSC Code: 12352200

General description: Manufactured for Sigma by Boston Biochem., Inc.

Application: 20S proteasome fraction from rabbit has been used as a positive control to determine proteasome activity.

Biochem/physiol Actions: Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP dependent process.

Biochem/physiol Actions: Catalytic core of the 26S proteasome that degrades polyubiquitinated proteins.

Physical form: Solution in 50 mM HEPES, pH 7.6, 150 mM sodium chloride, and 1 mM DTT, pH 7.6.