Synonyms: 2-Thiolanimine hydrochloride; 2IT; Dihydro-2(3H)-thiophenimine hydrochloride; Traut's reagent
Formula: C4H7NS · HCl
Formula Weight: 137.63
CAS No.: 4781-83-3
Purity: ≥98% (TLC)
Storage Temperature: 2-8°C
Application: Thiolating reagent for primary amines. Reacts at pH 7-10 by amidine bond to present free sulfhydryl. Useful in preparation of disulfide and/or thioether linked conjugates.
Other Notes: Note that the amidine linkage preserves original primary amine positive charge. Incorporates a five atom linker.
Packaging: 1 g in glass bottle
Packaging: 100, 500 mg in glass bottle
Assay: ≥98% (TLC)
Form: powder
Impurities: ≤5% Free sulfhydryl groups
MP: 198-201°C(lit.)
Solubility: H2O: soluble100 mg/mL
Storage Temp.: 2-8°C