2-C-Methyl-D-erythritol 4-phosphate lithium salt, >=98% (TLC)

Synonyms: MEP

CAS Number: 206440-72-4 (free acid)

Formula: C5H11O7P · xLi+

Formula Weight: 214.11 (free acid basis)

Linear Formula: C5H11O7P · xLi+

Purity: >=98% (TLC)

Storage: -20C

UNSPSC Code: 12352200

Application: 2-C-Methyl-D-erythritol 4-phosphate (MEP), the product of reductoisomerase IspC and first committed MEP pathway intermediate, is used to study the non-mevalonate MEP pathway for the biosynthesis of isoprenoids. MEP is used as a precursor for the synthesis of 4-diphosphocytidyl-2-C-methyl D-erythritol (CDP-ME), a key intermediate of the non-mevalonate pathway.

Biochem/physiol Actions: Metabolite intermediate specific to the non-mevalonate MEP pathway, generally found in prokaryotes, as precursor to isoprenoids as well as non-isoprenoids like vitamins. As this pathway is not present in humans, it is of interest for the development of bacterium-specific drugs in the search for treatments of infectious diseases.