Synonyms: (S)-1-Methyl-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazol-5-yl)-1H-indazole-5-carboxamide; Chemical Probe 92
Molecular Formula: C22H24N6O
Molecular Weight: 388.47
Linear Structural Formula: C22H24N6O
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: SGC-iMLLT (Chemical Probe 92) is a cell penetrant, potent and selective inhibitor of YEATS domain MLLT1/3 histone interaction. SGC-iMLLT downregulates MYC and DDN genes, while increases CD86 in MV4;11 AML cells.