Synonyms: N-(6-(3-(Cyclopropanesulfonamido)phenyl)-1H-indazol-3-yl)isobutyramide; SGC-AAK1-1 Negative Control
Molecular Formula: C20H22N4O3S
Molecular Weight: 398.48
Linear Structural Formula: C20H22N4O3S
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: SGC-AAK1-1N is a structure analog of and the recommended negative control for SGC-AAK1-1 (AAK1 IC50 = 11 muM and 270 nM, respectively, by coupled enzyme assay; KD = 8.8 muM/AAK1 & >10 muM/BIKE with SGC-AAK1-1N vs. KD = 26 nM/AAK1 & 930 nM/BIKE with SGC-AAK1-1). For characterization details of the active probe, SGC-AAK1-1, please visit the SGC-AAK1-1 probe summary on the Structural Genomics Consortium (SGC) website.SGC-AAK1-1, the active probe, is available from Sigma. To learn more about and purchase SGC-AAK1-1, click here.To learn about other SGC chemical probes, visit sigma.com/sgc