SDS (Sodium dodecyl sulfate)

Type: Anionic detergent Full Name: Sodium Dodecyl Sulfate Molecular Formula: C₁₂H₂₅NaO₄S Molecular Weight: 288.38 Form: White to off white powder Purity: >99% Solubility: Water Critical micelle concentration (CMC): 7-10mM (25°C) Aggregation number: 62 Cloud point: >100°C Average micellar weight: 18,000 SDS is also available as a 10% Solution or a 20% Solution

Applications

• An anionic detergent capable of almost complete disruption of cellular structures and denaturation.
• Used for solubilization of a wide variety of proteins, including membrane proteins, for electrophoretic separation.
• Detergent molecules tightly bind with the protein molecules masking their native charge and rendering the protein molecules the overall negative charge of the ionic detergent.