SDF-1alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1alpha is an 8.0 kDa protein containing 68 amino acid residues.
Synonyms: Stromal Cell-Derived Factor, CXCL12, SDF1A, TLSF-b, TPAR1, SDF-1b, TLSF
Application: Research Sub CategoryGrowth Factors & Receptors