Synonyms: 1-[4-(8-Oxa-3-azabicyclo[3.2.1]octane-3-sulfonyl)-phenyl]-3-pyridin-4-ylmethylurea; N-[4-(8-Oxa-3-azabicyclo[3.2.1]oct-3-ylsulfonyl)phenyl]-N'-(4-pyridinylmethyl)-urea
Molecular Formula: C19H22N4O4S
Molecular Weight: 402.47
Linear Structural Formula: C19H22N4O4S
MDL Number: MFCD32197237
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: SBI-797812 is a cell penetrant and potent activator of nicotinamide phosphoribosyltransferase (NAMPT) that increases intracellular levels of NMN and NAD+ in cells. SBI-797812 blocks binding of inhibitors to NAMPT and shifts the reaction equilibrium towards NMN formation. It elevates levels of NAD+ in mice liver.