Synonyms: 2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
Molecular Formula: C21H21BrN4O5
Molecular Weight: 489.32
Linear Structural Formula: C21H21BrN4O5
Purity: >=98% (HPLC)
Storage: -20C
Application: SBI-0206965 has been used to study its effect on the growth of cadmium-transformed prostate epithelial cells.
Biochem Physiol Actions: Since most of the tumor cells survive on autophagy mechanism, inhibition of autophagy inducers Unc-51 (serine/threonine-protein kinase)-like autophagy activating kinase (ULK1 and ULK2) might be useful in cancer therapy.