SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) and has been identified as increasing binding affinity to human and murine ACE2.
SARS-CoV-2 Spike protein (RBD, N501Y, His & Avi Tag ) carries polyhistidine and Avi tags at the C-terminus. It has high binding affinity to human chimeric ACE2 Fc (Cat. No. Z03484).
SARS-CoV-2 Spike protein (RBD, N501Y, His & Avi Tag) can bind with human ACE2 (Cat. No. Z03484) in functional ELISA assay.
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
Synonyms SARS-CoV-2 SP RBD, N501Y; 2019-nCoV SP RBD, N501Y
Description SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) and has been identified as increasing binding affinity to human and murine ACE2. SARS-CoV-2 Spike protein (RBD, N501Y, His & Avi Tag ) carries polyhistidine and Avi tags at the C-terminus. It has high binding affinity to human chimeric ACE2 Fc (Cat. No. Z03484).
Species SARS-CoV-2
Source Human
Tag His & Avi Tag
Biological Activity SARS-CoV-2 Spike protein (RBD, N501Y, His & Avi Tag) can bind with human ACE2 (Cat. No. Z03484) in functional ELISA assay.
Sequence Accession#QHD43416.1(Arg319-Ser591,N501Y)
Properties
- Molecular Weight Predicted on protein sequence: 30 KD
- Purity >90% as analyzed by SDS-PAGE
- Formulation Liquid Component PBS pH 7.4
- Storage Upon receiving, the product can be stored at -20°C or below. Please avoid repeated freeze-thaw cycles.
- Note For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.