SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) carries a Avi Tag followed by a polyhistidine tag at the C-terminus. It has high binding affinity to human chimeric ACE2.
SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) can bind with human ACE2 in functional ELISA assay.
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
Synonyms Lineage P.1; 20J/501Y.V3; VOC-202101/02; Brazil(ian) variant.
Description SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) carries a Avi Tag followed by a polyhistidine tag at the C-terminus. It has high binding affinity to human chimeric ACE2.
Species SARS-CoV-2
Source CHO
Tag C-terminus Avi & His Tag
Biological Activity SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) can bind with human ACE2 in functional ELISA assay.
Sequence Accession#QHD43416.1(Arg319-Ser591)(E484K, K417T, N501Y)
Properties
- Molecular Weight 30 KDa (predicted on protein sequence)
- Purity >90% as analyzed by SDS-PAGE Formulation Liquid Component PBS pH 7.4
- Storage Upon receiving, the product can be stored for 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles.
- Note For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.