Antigen: human S1P3 amino acids 12-25
Host: rabbit
Cross Reactivity: (+) human, mouse, and rat S1P3
Application(s): ICC and WB
S1P3 is one of five GPCRs that are activated by S1P. It couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and related signaling events. S1P3 is widely expressed in various tissues, suggesting diverse physiological functions of this receptor.