Synonyms: N-Boc-seco-CBI
Molecular Formula: C18H20ClNO3
Molecular Weight: 333.81
Linear Structural Formula: C18H20ClNO3
Purity: 95% (HPLC)
Storage: -20C
Application: N-Boc-CBI best used as its seco precursor (seco-N-Boc-CBI) is a simple alkylation subunit analog of that found in the naturally occurring antitumor agents the duocarmycins, yatakemycin, and CC-1065, which act by sequence selective DNA alkylation.
Other Notes: Design, Synthesis, and Evaluation of Duocarmycin O-Amino Phenol Prodrugs Subject to Tunable Reductive Activation