Synonyms: ((1R,3R,3'R)-3,3'-diethyl-3H,3'H-1,1'-spirobi[isobenzofuran]-7,7'-diyl)bis(diphenylphosphane); (R)-CrabPhos
Molecular Formula: C43H38O2P2
Molecular Weight: 648.71
Linear Structural Formula: C43H38O2P2
Purity: >=95%
Melting Point: 226-228 C
Application: (R,R,R)-SPIRAP is a chiral C2-symmetric spiroketal-containing ligand developed in the Nagorny lab for asymmetric catalysis. It can be used in variety of stereoselective transformations, including: Ir-catalyzed hydroarylation, Pd-catalyzed allylic alkylation, Pd-catalyzed Heck couplings, and Rh-catalyzed hydrogenation.
Other Notes: Design, Synthesis, and Application of Chiral C2-Symmetric Spiroketal-Containing Ligands in Transition-Metal Catalysis